Bettini Lab

Our laboratory investigates T cell development and function in the context of autoimmunity, cancer, and intestinal homeostasis. We are particularly interested in understanding regulatory (Foxp3+) T cell function and how this T cell population can be leveraged for treatment of autoimmunity and other disorders. ​

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Members of our laboratory utilize a number of cutting-edge techniques and models to ask how self-antigens and T cell receptors (TCRs) regulate T cell development and function. Links to protocols, including TCR retrogenic mice and multi-color flow cytometric spectral analyzer panels, can be found here.